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Quality 99.9% EGT Ergothioneine Crystalline Derived From Mushrooms Water Soluble OEM factory
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Quality 99.9% EGT Ergothioneine Crystalline Derived From Mushrooms Water Soluble OEM factory
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99.9% EGT Ergothioneine Crystalline Derived From Mushrooms Water Soluble OEM

Specifications
Highlight:

OEM EGT Ergothioneine

,

water Soluble EGT Ergothioneine

,

water Soluble l ergothioneine mushrooms

Molecularformula:
C9H15N3O2S
Appearance:
White To Off-white Crystalline
Dosageform:
Crystalline
Chemicalname:
Ergothioneine
Storagecondition:
Store In A Cool, Dry Place
Function:
Antioxidant, Cytoprotective Agent
Application:
Dietary Supplements, Cosmetics
Origin:
Naturally Derived From Mushrooms Or Synthesized
Stability:
Stable Under Normal Conditions
Productname:
EGT L-Ergothioneine
Solubility:
Soluble In Water
Key Attributes
Place of Origin: China
Minimum Order Quantity: 5KG
Price: $600-800/kg
Delivery Time: 7-15 work days
Payment Terms: TT
Product Description
L-Ergothioneine ≥99.9% Sleep Support Antioxidant Ingredient — OCTN-1 Transported EGT
Product Overview

Sleep difficulties are among the most commonly reported concerns in healthy aging — and DR.ERGO® L-Ergothioneine is the first antioxidant amino acid with direct clinical evidence for improving sleep onset in humans.

In a 16-week randomized, double-blind, placebo-controlled trial (147 adults, aged 55-79), the 25 mg/day EGT group recorded a statistically significant, dose-dependent reduction in sleep-onset difficulty, as measured by the Leeds Sleep Evaluation Questionnaire (LSEQ).

DR.ERGO® is produced by Anti-aging Ingredients LLC using patented green biofermentation technology (patented by the Chinese Academy of Sciences), yielding ≥99.9% purity in an ultra-stable crystalline form. Its active cellular uptake via the exclusive OCTN-1 transporter ensures efficient delivery to neural tissues, where it stabilizes the HPA axis, modulates neurotransmitter balance, and reduces neuroinflammatory signals that disrupt sleep architecture.

Specifications
Ingredient L-Ergothioneine (EGT)
Purity ≥99.9%
Form Ultra-stable crystalline powder
Production Method Green biofermentation (patented, Chinese Academy of Sciences)
Cellular Transporter OCTN-1 exclusive active transport
Recommended Daily Dose 8-25 mg (per clinical evidence)
Allergen Status Allergen-free
Certifications FDA GRAS / EU Novel Food / NSF GMP / ISO 22000 / Halal / Vegan
Applications Tablets, Capsules, Gummies, Gels, Powders, Jellies
Key Characteristics
  • Clinically proven sleep onset improvement at 25 mg/day in a 16-week RCT (LSEQ-validated)
  • Exclusive OCTN-1 active cellular transporter — superior bioavailability versus passive-uptake antioxidants
  • Ultra-stable crystalline form — excellent shelf life under standard storage conditions
  • 5-mechanism action: neurotransmitter balance, oxidative stress reduction, HPA axis stabilization, brain energy metabolism, neuroinflammation attenuation
  • FDA GRAS approved, EU Novel Food listed — compliant for North American and European supplement markets
Frequently Asked Questions
What clinical evidence supports DR.ERGO® for improving sleep?
A peer-reviewed 16-week randomized, double-blind, placebo-controlled trial published in Nutraceuticals (2025) demonstrated that the 25 mg/day EGT group showed a significant, dose-dependent improvement in sleep onset as measured by the Leeds Sleep Evaluation Questionnaire. A separate Japanese RCT also confirmed that 20 mg/day EGT significantly improved both subjective and objective sleep quality (EEG-measured) over 4 weeks.
Why does the OCTN-1 transporter matter for bioavailability compared to other antioxidants?
Unlike antioxidants that rely on passive diffusion (which limits cellular concentration), EGT is actively transported into cells via OCTN-1 — a dedicated cellular uptake protein widely expressed across organs including the brain, liver, and kidneys. This results in efficient accumulation and retention in tissues, with less than 4% of an oral dose excreted in urine. No other known dietary antioxidant has a similarly dedicated transport mechanism.
Can DR.ERGO® be combined with melatonin or other sleep ingredients?
DR.ERGO® acts through neuroregulatory and antioxidant pathways rather than sedative mechanisms, making it compatible with melatonin, GABA, and other sleep support actives. As always, we recommend consulting formulation specialists and relevant regulatory guidance for combination products.
What dosage forms are available and what is the recommended inclusion level?
DR.ERGO® is available as a bulk crystalline powder for formulation into tablets, capsules, gummies, gels, powders, and jellies. Clinical trials support effective use at 8-25 mg per daily serving. Exact inclusion levels depend on product format and target claim.
Overall Rating
5.0
★★★★★
★★★★★
Based on 50 reviews recently
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All Reviews
  • S
    Sharry
    China (Mainland) May 20.2026
    ★★★★★
    ★★★★★
    The L-ergothioneine supplied by Shanghai EGT Synbio Group offers good solubility and is supported by comprehensive stability data, providing strong support for the quality-control system of our sports nutrition products.
  • L
    l*a
    China (Mainland) May 13.2026
    ★★★★★
    ★★★★★
    During ingredient screening, Shanghai EGT Synbio Group's product performed strongly in purity and batch-to-batch consistency, making the company one of our preferred ingredient suppliers.
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