Shanghai EGT Synbio Group Co., Ltd. is a synthetic biology company specializing in high-purity bioactive ingredients for healthy aging.
Established in 2016, the company has built integrated capabilities in strain development, enzyme engineering, high-density fermentation, biocatalysis, purification and crystallization.
Its ingredient portfolio is led by Dr.Ergo® L-Ergothioneine 99.99%, together with Spermidine and S-Equol, serving dietary supplement, functional food, beverage and personal care applications.
Dr.Ergo® is developed for research-led formulations in healthy aging, antioxidant support, cellular protection, mitochondrial function, cognitive wellness and oral beauty.
Shanghai EGT Synbio Group supports global brand owners, formulators, manufacturers and distributors with standardized ingredients, scalable supply, quality documentation, regulatory support and formulation services.
Dr.Ergo® L-Ergothioneine is supported by internationally recognized regulatory documentation, including U.S. FDA GRAS, Independent Self-GRAS, Canadian NHP, and compliance with the EU Novel Food framework. S-Equol has also completed an Independent Self-GRAS determination, providing strong regulatory support for compliant product development and commercialization.
Committed to scientific excellence and regulatory compliance, Shanghai EGT Synbio Group Co., Ltd. provides globally trusted, high-quality, traceable ingredients together with comprehensive technical and formulation support for partners worldwide.
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Email:sales@ygingredients.com
Shanghai EGT Synbio Group Co., Ltd. is committed to providing global customers with one-stop solutions ranging from active ingredient R&D and production to application support. Powered by synthetic biology technologies, the company leverages proprietary techniques including enzyme directed evolution, high-density fermentation, high-efficiency enzymatic catalysis, purification and crystallization to produce L-(+)-ergothioneine of exceptional purity and safety. Our products are widely applied in functional foods, dietary supplements, premium personal care products and pharmaceuticals. We also offer customized formulation recommendations, quality control testing and regulatory compliance support to accelerate our customers' time-to-market.
The company initiated its R&D project in 2016, focusing on green fermentation technology for ergothioneine. From 2016 to 2020, we achieved successive breakthroughs in strain screening, fermentation processes and purification technologies, reaching a product purity of 99.99%. In 2021, we completed a fully automated fermentation production line and achieved stable mass production, with product quality reaching internationally leading standards and our green manufacturing system fully implemented.
Team & Scientific Leadership
Shanghai EGT Synbio Group Co., Ltd. is driven by a multidisciplinary R&D team dedicated to the development and industrialization of innovative bioactive ingredients. Our core team includes 10 key professionals, including 2 Ph.D. holders and 5 M.S. holders, many with academic backgrounds from the Chinese Academy of Sciences and other leading universities in China.
Supported by over 2,000 m² of advanced R&D facilities, the team combines expertise in synthetic biology, enzyme engineering, biofermentation, and process development to deliver high-purity, science-backed ingredients for global health and nutrition markets.
Scientific Advisory Committee (SAC)
Our Scientific Advisory Committee (SAC) brings together internationally recognized experts in synthetic biology, food science, healthy aging, and bioactive ingredient research. Working closely with our R&D team, the committee provides strategic scientific guidance for the development and global application of L-Ergothioneine, Spermidine, and S-Equol.
Prof. Long Lu, Ph.D.
Research Professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

A distinguished scientist and recipient of the National Science Fund for Distinguished Young Scholars, Prof. Long Lu provides strategic guidance on technology innovation and the industrialization of longevity ingredients, including DR.ERGO® L-Ergothioneine.
Prof. Liang Lin, Ph.D.
Research Professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

Prof. Liang Lin specializes in enzyme engineering, synthetic biology, and biocatalytic process development. His research focuses on enzyme discovery and biomanufacturing technologies that support the efficient production of high-value bioactive ingredients, contributing to the development of next-generation longevity solutions.
Prof. Robert B. Beelman, Ph.D.
Professor Emeritus of Food Science, The Pennsylvania State University

Prof. Robert B. Beelman is an internationally recognized expert in mushroom nutrition and ergothioneine research. He was among the first scientists to propose L-Ergothioneine as a potential "Longevity Vitamin" and has dedicated his research to its role in healthy aging, oxidative stress protection, and chronic disease prevention. His work has significantly advanced global scientific understanding of ergothioneine and its nutritional importance.