Newly Certified | Why Is EquoPro® S-Equol Trusted by the Industry When Up to 65% of Women Cannot Naturally Produce It?
At the 2026 Oral Anti-Aging Ingredients Trends & Application Innovation Forum, EquoPro® S-Equol, the flagship ingredient from Shanghai EGT Synbio Group Co., Ltd., received prestigious industry recognition:
🏆 2026 Oral Food Product Innovation Certification
(Jointly Presented by Food Data Link and FIA Food Ingredients Exhibition)
Food Data Link is a leading industry media platform and award organization in China's food and nutrition sector. Its evaluation process is known for its rigor, with entries assessed through multiple rounds of expert review based on ingredient innovation, scientific evidence, regulatory compliance, and commercial viability, rather than marketing exposure alone.
The joint recognition from both FDL and FiA (Food Ingredients Asia) further underscores EquoPro®'s leadership in the oral anti-aging ingredient sector.
The award-winning EquoPro® S-Equol is a targeted functional ingredient developed by Shanghai EGT Synbio Group Co., Ltd. to support healthy ovarian aging in women aged 35 and above. It has successfully completed the U.S. Self-GRAS safety assessment, demonstrating its safety for use in dietary supplement applications.
S-Equol is the biologically active metabolite of soy isoflavones produced in the human body. Owing to its molecular structure, which closely resembles that of endogenous estrogen, S-Equol can selectively exert estrogen-like activity in a gentler and safer manner than conventional hormone therapy. Unlike traditional hormone replacement therapy (HRT), S-Equol is well tolerated and is not associated with the increased risks of thrombosis or breast cancer typically linked to hormone-based treatments. Clinical studies have demonstrated that S-Equol may help alleviate five of the most common menopause-related concerns, including hot flashes, bone loss, skin aging, mood fluctuations, and muscle and joint discomfort.
S-Equol is the bioactive metabolite of soy isoflavones produced by specific gut bacteria, with biological activity considered greater than that of soy isoflavones themselves. However, only about 30% of the global population naturally harbor the gut microbiota capable of producing S-Equol. In other words, for the majority of people, consuming soy or soy isoflavones alone may not result in endogenous S-Equol production or its associated physiological benefits.
This is precisely where direct S-Equol supplementation offers a compelling scientific solution. According to the World Health Organization (WHO), an estimated 1.1–1.2 billion women worldwide are expected to be in menopause by 2030, including more than 210 million women in China. While hormone replacement therapy (HRT) remains an important treatment option, it is not suitable for everyone.
As a result, there is growing demand for safe, science-backed, non-hormonal alternatives to support women's health during menopause. EquoPro® S-Equol is designed to address this unmet need by providing a targeted, evidence-based solution for healthy menopausal support.
Leveraging the cutting-edge scientific expertise of the Chinese Academy of Sciences, we have developed a bio-fermentation process capable of producing 99% high-purity S-Equol at scale, overcoming the solvent residue concerns and production limitations associated with plant extraction.
Stable. Pure. Accessible. Bringing a scientifically validated molecule to brand owners with consistent quality is what gives us the greatest sense of achievement as an ingredient manufacturer.
Leading brands such as FineNutric and CAACBB have already incorporated EquoPro® S-Equol into their flagship formulations, demonstrating strong confidence in its formulation stability and market acceptance.
CAACBB Chaoyanqing (Wumeiniang) Feicui S-Equol Powder Stick PacksEquoPro® S-Equol is suitable for a wide range of dosage forms, including softgels, hard capsules, compressed tablets, orally disintegrating tablets (ODTs), and functional beverages. It can also be formulated synergistically with ingredients such as L-ergothioneine, spermidine, and ceramides to create differentiated women's healthy aging products.
For brands seeking the next-generation active ingredient for women's oral health, EquoPro® offers a science-backed, market-ready solution for product innovation.
About Shanghai EGT Synbio Group Co., Ltd.
Shanghai EGT Synbio Group Co., Ltd. is a high-tech enterprise specializing in synthetic biology and biotransformation technologies, with a focus on the research, development, and manufacturing of natural active ingredients for healthy aging.
The company has established a portfolio of four flagship ingredients: Dr.Ergo® L-Ergothioneine, a benchmark antioxidant ingredient; EquoPro® S-Equol, developed to support healthy ovarian aging in women; Dr.SPD® Spermidine, designed to support cellular renewal and healthy aging; and HariCera™ Elastic Ceramide, an innovative ingredient for oral beauty and skin health.
Produced through advanced biomanufacturing technologies, all four ingredients are manufactured at high purity and are supplied to leading global brands in dietary supplements, functional nutrition, and personal care.
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